Caution is warranted for a few reasons:

  1. I've been told that the liver uses methylfolate for detoxification. If you take too much too soon, or ramp up too quickly, you will end up really feeling like hell because of the detoxification process. This may be more of a problem for people who have toxins built up in their system due to inefficient detoxification.

  2. I've been told that methylfolate can increase your blood pressure. Your doctor may need to be monitoring this.

  3. I've been told that if you do need all three of methylfolate, methylcobalamin and a homocysteine regulator but do not get all three, or if you get them in the wrong amounts, treatment can be ineffective (the risk here is that you will become disheartened and give up on a treatment that could have changed your life).

  4. I've been told that if your digestive system is a mess, you may need to fix it up before the treatment will work. Once again, the risk is becoming disheartened and missing out on a useful treatment.

  5. Other reasons I may not know about because I am not a medical professional.

You have to remember, everything is connected - your body is a system. A very, very complicated system. Change one thing over here, and there can be unforeseen consequences over there.

Unfortunately, doctors are tasked with the unrealistic expectation of learning about thousands of diseases and thousands of symptoms and trying to match each disease to each symptom... and, on top of that, all of them are complicated to treat... to be really honest, I don't think it is possible for any human to do a good job of diagnosing every disease, or treating every problem. From what I've seen, when people use the "throw a doctor at it" approach, it can fail pretty hard pretty often. What you want is the "find the exact right doctor for this specific problem" approach. Don't expect a GP to solve everything you bring to them. Instead, find someone who specializes in your set of symptoms or diagnosis and has lots of experience with it. That's much more likely to get you a functional treatment plan.

Public Service Announcement Collection

by Eliezer Yudkowsky 1 min read27th Jun 2013330 comments

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P/S/A:  There are single sentences which can create life-changing amounts of difference.

  • P/S/A:  If you're not sure whether or not you've ever had an orgasm, it means you haven't had one, a condition known as primary anorgasmia which is 90% treatable by cognitive-behavioral therapy.
  • P/S/A:  The people telling you to expect above-trend inflation when the Federal Reserve started printing money a few years back, disagreed with the market forecasts, disagreed with standard economics, turned out to be actually wrong in reality, and were wrong for reasonably fundamental reasons so don't buy gold when they tell you to.
  • P/S/A:  There are many many more submissive/masochistic men in the world than there are dominant/sadistic women, so if you are a woman who feels a strong temptation to command men and inflict pain on them, and you want a large harem of men serving your every need, it will suffice to state this fact anywhere on the Internet and you will have fifty applications by the next morning.
  • P/S/A:  Most of the personal-finance-advice industry is parasitic and/or self-deluded, and it's generally agreed on by economic theory and experimental measurement that an index fund will deliver the best returns you can get without huge amounts of effort.
  • P/S/A:  If you are smart and underemployed, you can very quickly check to see if you are a natural computer programmer by pulling up a page of Python source code and seeing whether it looks like it makes natural sense, and if this is the case you can teach yourself to program very quickly and get a much higher-paying job even without formal credentials.