People hear about a gamble involving a big payoff, and dismiss it as a form of Pascal's Wager. But the size of the payoff is not the flaw in Pascal's Wager. Just because an option has a very large potential payoff does not mean that the probability of getting that payoff is small, or that there are other possibilities that will cancel with it.
Discuss the post here (rather than in the comments to the original post).
This post is part of the Rerunning the Sequences series, where we'll be going through Eliezer Yudkowsky's old posts in order so that people who are interested can (re-)read and discuss them. The previous post was What Do We Mean By "Rationality"?, and you can use the sequence_reruns tag or rss feed to follow the rest of the series.
Sequence reruns are a community-driven effort. You can participate by re-reading the sequence post, discussing it here, posting the next day's sequence reruns post, or summarizing forthcoming articles on the wiki. Go here for more details, or to have meta discussions about the Rerunning the Sequences series.