Now you can donate to Singularity Institute using Bitcoin.
Currently Bitcoin mining appears to be profitable as only bubble economics can be. Already some Less Wrong users have purchased GPUs and started mining Bitcoin. Please consider sending some Bitcoins to SI at address 1HUrNJfVFwQkbuMXwiPxSQcpyr3ktn1wc9
2014 Edit: Please donate Bitcoin by using the Bitpay link on MIRI's donate page. Thanks!
Apparently that's old. The address currently on their website is https://blockchain.info/address/1BszW45pwXx7d7g4x9Xxbs9MGJEQcJsd3v although that hasn't received any coins yet.
Maybe the old one is fine too, but unless someone can shed light on why they changed from the old address, it's probably best not to send coins to it, although I'd hope if it had become unsafe they would have announced it loudly.