While I wasn't at 80% of a lab leak when Eliezer asseted it a month ago, I'm now at 90%. It will take a while till it filters through society but I feel like we can already look at what we ourselves got wrong.
In 2014, in the LessWrong survey more people considered bioengineered pandemics a global catastrophic risk then AI. At the time there was a public debate about gain of function research. On editoral described the risks of gain of function research as:
Insurers and risk analysts define risk as the product of probability times consequence. Data on the probability of a laboratory-associated infection in U.S. BSL3 labs using select agents show that 4 infections have been observed over <2,044 laboratory-years of observation, indicating at least a 0.2% chance of a laboratory-acquired infection (5) per BSL3 laboratory-year. An alternative data source is from the intramural BSL3 labs at the National Institutes of Allergy and Infectious Diseases (NIAID), which report in a slightly different way: 3 accidental infections in 634,500 person-hours of work between 1982 and 2003, or about 1 accidental infection for every 100 full-time person-years (2,000 h) of work (6).
A simulation model of an accidental infection of a laboratory worker with a transmissible influenza virus strain estimated about a 10 to 20% risk that such an infection would escape control and spread widely (7). Alternative estimates from simple models range from about 5% to 60%. Multiplying the probability of an accidental laboratory-acquired infection per lab-year (0.2%) or full-time worker-year (1%) by the probability that the infection leads to global spread (5% to 60%) provides an estimate that work with a novel, transmissible form of influenza virus carries a risk of between 0.01% and 0.1% per laboratory-year of creating a pandemic, using the select agent data, or between 0.05% and 0.6% per full-time worker-year using the NIAID data.
Even at the lower bar of 0.05% per full-time worker-year it seems crazy that society continued playing Russian Roulette. We could have seen the issue and protested. EA's could have created organizations to fight against gain-of-function research. Why didn't we speak every Petrov day about the necessity to stop gain of function research? Organizations like OpenPhil should go through the 5 Why's and model why they messed this up and didn't fund the cause. What needs to change so that we as rationalists and EA's are able to organize to fight against tractable risks that our society takes without good reason?
This is obviously not the right calculation, and I expected better from a rationalist. I've already counted the fact that it started in Wuhan where they happen to have a biosafety 4 lab studying coronaviruses as the strongest evidence in favor of the leak. You may feel I didn't count it strongly enough, but that's a different argument. What does the entire population of China have to do with it after that point? Nothing. You're being completely arbitrary by drawing the boundary there. Why not the entire world?
The population of Wuhan, maybe, but we can probably narrow it down more than that, and then we also have to account for the fact that the WIV employees would be much more likely to report anything out of the ordinary when it comes to illness. For the rest of Wuhan at the time, the most common symptoms would have been reported as "the flu" or "a cold". Mild cases are common, and at least a third of people have no noticeable symptoms at all, especially early on with the less virulent original variant.
The population of Wuhan is about 8.5 million, and the number of staff at WIV, I think was more like 600. So that's more like 14,000 : 1. I think WIV staff could be easily 20x more likely to notice that the disease was novel, so that's more like 700 : 1. That's still pretty strong evidence, but nowhere near what you're proposing.