there are assumptions that go into this calculation, of course. the most important ones are the mutation is dominant and that the population size is constant. if the populations size is decreasing, the fixation probability goes down, and vice versa. deviation from dominance as well decreases the fixation probability.

Probability of fixation = 2sthere are assumptions that go into this calculation, of course. the most important ones are the mutation is dominant and that the population size is constant. if the populations size is decreasing, the fixation probability goes down, and vice versa. deviation from dominance as well decreases the fixation probability.