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I just donated $5,000 to your fund at the Society of Venturism, as promised.

Like Stephan, I really hope you make your goal.

This concerns me (via STL): Automatic Revocation of Exemption Information

The federal tax exemption of this organization was automatically revoked for its failure to file a Form 990-series return or notice for three consecutive years. The information listed below for each organization is historical; it is current as of the organization's effective date of automatic revocation. The information is not necessarily current as of today's date. Nor does this automatic revocation necessarily reflect the organization's tax-exempt or non-exempt status. The organization may have applied to the IRS for recognition of exemption and been recognized by the IRS as tax-exempt after its effective date of automatic revocation. To check whether an organization is currently recognized by the IRS as tax-exempt, call Customer Account Services at (877) 829-5500 (toll-free number).

Do you think your strategy is channeling more money to efficient charities, as opposed to random personal consumption (such as a nice computer, movies, video games, or a personal cryonics policy)?

A more positive approach might work well: donate for fuzzies, but please extrapolate those feelings to many more utilons. I just used this technique to secure far more utilons than I have seen mentioned in this thread, and it seems like it might be the most effective among the LW crowd.

More and more, if I can do anything about it. (Edit since someone didn't like this comment: That's a big if. I'm trying to make it smaller.)

I'll be in Seattle in two weeks, and I'll take care of it (final three paragraphs).

Kim, I am so sorry about what has happened to you. Reading your post was heartbreaking. Death is a stupid and terrible thing.

Like JGWeissman, I planned to donate $500.

Stephan has been a close friend of mine for the past decade, and when he told me he was planning to donate $5,000, I wrangled a commitment from him to do what I do and donate a significant and permanent percentage of his income to efficient charities. There are many lives to save, and even though you have to do some emotional math to realize how you should be feeling, it's the right thing to do and it's vital to act.

He wrangled a commitment from me too: when CI manages a fund for you, I will donate $5,000.

If you're planning on it, you should get on it now. Cryonics is much more affordable if you don't have a terminal illness and can cover it with a policy.

People will give more to a single, identifiable person than to an anonymous person or a group.

As a counterpoint to your generalization, JGWeissman has given 82x more to SIAI than he plans to give to this girl if her story checks out.

No matter which study I saw first, the other would be surprising. A 100k trial doesn't explain away evidence from eight trials totaling 25k. Given that all of these studies are quite large, I'm more concerned about methodological flaws than size.

I have very slightly increased my estimate that aspirin reduces cancer mortality (since the new study showed 7% reduction, and that certainly isn't evidence against mortality reduction). I have slightly decreased my estimate that the mortality reduction is as strong as concluded by the meta-analysis. I have decreased my estimate that the risk tradeoff will be worth it later in life. I have very slightly increased my estimate that sick people are generally more likely to develop cancer and aspirin is especially good at preventing that kind of cancer, but I mention that only because it's an amusingly weird explanation.

If this new study is continued with similar results, or even if its data doesn't show increased reduction when sliced by quartile (4.6, 6.0, 7.4 years), I would significantly lower my estimate of the mortality reduction.

I'll continue to take low-dose aspirin since my present risk of bleeding death is very low, and if the graphs of cumulative cancer mortality reduction on p34 of the meta-analysis reflect reality, I'll be banking resistance to cancer toward a time when I'm much more likely to need it. I can't decide to take low-dose aspirin retroactively.

The meta-analysis you cite is moderately convincing, but only moderately. They had enough different analyses such that some would come out significant by pure chance.

Their selection methodology on p32 appears neutral, so I don't think they ended up with cherry-picked trials. Once they had their trials, it looks like they drew all conclusions from pooled data, e.g. they did not say "X happened in T1, Y happened in T2, Z happened in T3, therefore X, Y, and Z are true."

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