Indeed, there is a huge potential for dangerous applications with current technology. It is easier to design a molecule to poison a system than to heal a system.

Thanks, I updated the article. Working on Part II now.

I totally agree. The techniques that have worked well so far are quite far from understanding cells, organs, organisms, or ecosystems. However, the incredible rate of progress at the small molecule to protein complex scale is already showing a strong impact, at least on getting a much better funnel before we begin in vivo testing.

I'm very surprised that there is no mention of a low-dose aspirin regime here. Low dose aspirin can greatly reduce chances of stroke, heart attack, and cancer. The main caveat is that there is increased chance of bleeding or stomach ulcer, the latter of which can be avoided by taking with food.

We make it up as we go along :)

Basically my wife and I ask ourselves "What is the next thing to learn, or what do the kids need to review?" Our very broad curriculum for math is operations in order, from addition to exponents and logarithms, with learning and graphing functions that use that operation at the same time. So, when they learn addition they learn linear functions and line graphing, curves when they learn exponents, etc. Then fractions and decimals, because you need to understand fractions to understand the unit circle, which is the basis for angles and therefore geometry and trig. Reading is easiest: make them read and discuss harder books than they read last week. Writing is similarly straightforward, though there we reach rhetorical techniques when we do persuasive writing, meter when we write poetry, etc. History we are doing linearly, and trying emphasize the history of technological progression and cultural progression over dates and names. For example, kids should know what the difference between neolithic and paleolithic societies is, or what the limitations of bronze tooling are. We also do a lot of timelines, so the kids know about the different states of various societies at the same time in history.

Finally, the best thing about this approach is that you can get your teachers to suggest things that would work well in your curriculum, or related areas that should be taught together. If you ever get anxious about missing something you can look up your local curriculum standards, though most often these will just show you how ridiculously ahead of public school the kids are.

Do what Harry's dad in HPMOR does: hire local grad students to be homeschool tutors. I do this for my 6 year old and 9 year old, and it is awesome. We parents do very high-level curriculum, taking about half an hour each week, and the tutors and kids do the rest. Teach at the kids' pace, choose material and progressions that make sense to you (or make sense to him), and have constant contact with teachers. I've found $20/hour is an attractive wage for most PhD students, and their expertise means that the barrage of "why?" questions the kids ask can actually be answered, often with current research findings. We've found we can cover 2 to 4 times the material in public school curriculum, and school is from 9 to 2. Also, you can do reasonable things like teach radians before degrees, graphing and functions along with each operation, foreign languages with native speakers, and Greek and Roman roots starting in kindergarten.

Hi there, I'm a Biologist turned Software Engineer, age 34. I came to Less Wrong through Overcoming Bias and HPMOR, and I'm still here because the notions of rationality appeal to me. It is nice to among others who hold rationality as an ideal to aspire to.