Do you have any idea of how to use FTP as a proxy if one cares about longevity? I have a bike so installing a power meter would be way easier than doing V02 max tests and the calculator you provided is too coarse to give me confidence that I'm hitting thresholds I want to hit.
Would love that! You can send them to the email above, comment here, whatever works for you.
1update please!
This is cool. I asked it a question in a field I'm not knowledgable about at all but my roommate is. I think having the structure there to make it maximally easy to elicit his expertise is super valuable.
1Wow, somewhere along the way I got the impression that MIRI is a quiet org that occasionally speaks loudly… so much so that I never thought to check if they put out a newsletter.
It was gluten.
This is shockingly similar to what I'm going through. And the fries that fucked me up the other night are indeed fried in canola oil. I'm cautiously optimistic but I know how complicated these things can be -_-. Will report back!
1Ok so modulo @GeneSmith's comments about this gene potentially being red herring, if there were a genetic basis to this, we'd expect to see prevalance of this trait increase due to genetic drift and removal of the selection pressure right?
I don't have a good sense of how quickly we'd expect to be able to detect those population level differences with the rate at which calories have become more available and the rate of growth of the variant.
Figure 7 in @guzey's post shows that it's directionally been increasing but a lot has changed about our environments and lifestyles so it doesn't rule out that maybe people are in-fact less pre-disposed to sleep but something else is increasing it.
https://www.lesswrong.com/posts/HvcZmKS43SLCbJvRb/theses-on-sleep
Since the matter at hand is a genetic basis that could flip a switch to needing "a lot less sleep" we should still expect to see the variance in sleep duration increase in the population even if the mean is increasing. I have no idea what the data says about that though.
That matrix goes a long way in showing that there isn't much correlation between diseases in the natural distribution. What is the reason to believe those correlations will remain low when you are making edits resulting in an extremely unlikely genome?
I believe I have a bug-free implementation of this here, but I will reward anyone who does find a bug and can fix it. Something more than $10 but less than $50 depending on how much you are just pointing out a problem vs going into the code to fix it.