Even after solving aging, we're susceptible to death by accident, disease, and murder. Are there other research directions for achieving extremely long lifespans (at least 1,000-10,000 years)?

Even if they're not popular, does anyone have an idea they think would work? The best I've been able to come up with after thinking about it for 10 minutes is an isolated brain, which would require us to figure out how input/output channels to the brain work (or at least be able to reverse-engineer the ones we already have), keep an isolated brain alive and functioning reliably for indefinite amounts of time (we've made some progress here even with little interest: one, two), and focus all of medicine into curing diseases of the brain.

Anyway, please reply with your best approaches and ideas.

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