Holden Karnofsky is a co-founder of effective altruism, and pioneered GiveWell.
He was the CEO of Open Philanthropy, but left in April 2024 to become a Visiting Scholar at the Carnegie Endowment for International Peace to work on international security risks from advances in artificial intelligence. He joined Anthropic as a member of technical staff on January 2025.
In May 2012, Karnofsky posted Thoughts on the Singularity Institute (SI), which became the most-upvoted article ever on Less Wrong. It offered a detailed critique of what is now the Machine Intelligence Research Institute, and spawned a great deal of discussion.
MIRI staff posted two replies:
Paul Crowley ("ciphergoth") posted discussion articles for each point raised:
Other discussion: