This would likely be true of many other (hard) drugs if there had been a history of legally selling them instead of nipping their markets in the bud. In fact, this would probably be true of wireheading too if it was practical, and ultimately, orgasmium. Willing to bite that bullet?
Go one step farther. Do that compulsion to agree and be mellow with people you don't agree with mean you're a dishonest jerk who's trying to manipulate them, or does it mean you're not feeling comfortable with disagreeing with them (for instance because you feel like they'd reject you if you did, which might be painful, or because you do not want to hurt their feelings, or because you feel like you don't have the social status to do that). Don't necessarily assume you're evil.
For instance I know I hate lying mostly because I am feeling insecure enough to ... (read more)
Quite a few associations rooted in transhumanism have attempted (whether they did so successfully is questionable) to distance themselves from the crazy-sounding (to a mainstream audience) plain description of their original goals and beliefs, in an effort to attract more and better quality funding and following (such as academia).
and I have seen Fermi estimates for quantities like e.g. the mass of the Earth apparently extract narrow and correct estimations out of the sums of multiple widely erroneous steps.