Well, there's even another option. Low-hanging fruit (since it's pretty likely anyways), but I'd guess that you have an O blood type? O blood types have the lowest monoamine oxidase activity, which suggests that they will be slow to breakdown catecholamines, such as adrenaline which caffeine stimulates. I'm an O blood type, and anecdotally, coffee could easily interfere with my sleep even when drunk in the morning. I also had paraxanthine for the first time today (which is why I'm here) with a 300mg dose from an Update energy drink, and it doesn't seem to be interfering with sleepiness like caffeine would for me. Not sure what that means.
Well, there's even another option. Low-hanging fruit (since it's pretty likely anyways), but I'd guess that you have an O blood type? O blood types have the lowest monoamine oxidase activity, which suggests that they will be slow to breakdown catecholamines, such as adrenaline which caffeine stimulates. I'm an O blood type, and anecdotally, coffee could easily interfere with my sleep even when drunk in the morning. I also had paraxanthine for the first time today (which is why I'm here) with a 300mg dose from an Update energy drink, and it doesn't seem to be interfering with sleepiness like caffeine would for me. Not sure what that means.