Brooster

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Omicron Post #10

Hello,

Firstly, I follow your CoViD posts with great interest, and would like to say thank you very much for the work you put into this project. 

I wanted to direct you to the Colorado state CoViD data portal, which I only recently discovered. I saw that you've included Washington state data and thought it might help to have an easy visual reference to compare states/regions. It contains a fair amount of data the state collects on various aspects of the pandemic; healthcare impact, testing, cases, etc. Of note is the variant surveillance data; a week-by-week graphic for relative proportions of variants is available, and is very illustrative particularly of the spread of Omicron. The comparison to Delta is fairly stark; Omicron has approached fixation more than twice as fast as Delta in the state. The sequencing sampling methodology could lend itself to imprecision (only a small proportion of positives are sequenced), and much of the data provided upfront is aggregated over the entire course of the pandemic for some reason, but there may be something of value either on this page or the various resources provided therein:

https://covid19.colorado.gov/data

Once again, thank you for these posts, and I hope this will be of some use.

What other peptide vaccines might it be useful to make?

Gum disease. While oral pathogens are mostly bacteria, they're also excellent at evading and even subverting the natural immune response. Considering the likelihood that human diets will continue to contain large amounts of carbohydrates for the foreseeable future, gum disease represents a very large and growing cause of both morbidity and economic burden for people in all economic situations. Targeting key bacterial species or even maladaptive human immune activity could save everyone money, pain, and increase the day-to-day well-being of a majority of humans in perpetuity.