This is beautiful. Thank you.
Hi! It's time to convert my lurking into an active account. I'm interested in all things related to making the long-term future go well, and I currently run Future Forum.
This is amazing, thank you!
We are excited to announce Future Forum, an experimental 4-day conference taking place Aug 4-7 in San Francisco. We want to gather promising people from across communities interested in the long-term future of humanity, introduce them to one another, reflect on transformative technologies and their far-reaching consequences (upside and downside risks), and then generate new promising and thoughtful projects across this cross-community ecosystem. We expect around 250 attendees.
We’re putting special emphasis on mingling EA and Silicon Valley tech. We think that Silicon Valley contains promising talent that does or could work on pressing problems with agency and ambition, but that it could also benefit from EA-inspired thoughtfulness about impact and about downside risks of working on transformative technologies. On the flip side, we believe that EA could generally...
This is an awesome self-experiment. Sadly the 100ug dose used might be too low by at least an order of magnitude. How was it chosen?
- We've been doing extensive placebo-controlled preclinical mouse trials with orexins and stabilized orexins in the last 6 months. Typically, we use 1 - 1000 ug per mouse per dose. We've found that 100ug intranasally is our common effective dose in mice, to achieve measurable behavioral effects such as improved wakefulness or increased locomotion.
- Happy to share more preclinical research data here privately.
- Scaling drug dosing
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