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henryaj
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Why you should be using a retinoid
henryaj10mo30

https://www.sciencedirect.com/science/article/pii/S1015958423001392 suggests that bright light might be causing the effect, not UV.

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Why you should be using a retinoid
henryaj10mo30

That's an interesting paper! Although it seems a bit confounded - "Because eyes of mice and of human volunteers were not covered, we cannot exclude the possibility that solar/UV radiation to the eye affected the observed sexual behavior." Which would be interesting if true, suggesting that just being outside and getting UV light in the eyes would be the thing to do. I guess you note this at the end of your first comment.

What do you think about the potential skin aging effects of UV vs the potential health benefits?

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Why you should be using a retinoid
henryaj10mo11

There's plenty of scientific evidence for the effectiveness of topical retinoids, going back several decades.

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Dear Self; We Need To Talk About Social Media
henryaj4y30

This is wonderful; thank you for writing it. Very much enjoyed the exposition of the "Quiet" state; have been trying out your advice of switching everything off and trying to slip into such a state and am enjoying what I've found there.

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Omicron Post #4
henryaj4y10

Likewise, thanks for all you're doing Zvi.

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Omicron Post #4
henryaj4y10

Sure enough, the UK has triggered its "Plan B" which mandates working from home for those who can, plus vaccine passports for big events. Perhaps suggests lockdowns coming in the new year.

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Omicron Variant Post #1: We’re F***ed, It’s Never Over
henryaj4y20

Do you know what kind of research Theodora's lab is actually doing? (She doesn't have a surname on Twitter so I can't find her). But I imagine research into spike protein mutants could just involve synthesising spike protein that has mutations and assaying the binding affinity of antibodies to the synthetic spike protein – not necessarily creating mutated viruses.

(undergrad biochemistry was a long time ago. I could well be wrong)

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Making Vaccine
henryaj4y40

I also don't understand her comments about the peptide 'not neutralising COVID in cell [culture]' - why would it? The peptide is just an antigen to get the body to raise an immune response; on its own it doesn't kill COVID.

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Covid 12/24: We’re F***ed, It’s Over
henryaj5y10

Not the OP so can't answer for him, but qualitatively the second (November) lockdown was quite different from the first (March) lockdown - much more leeway given on exercising outdoors, workplaces largely stayed open (even if people were working from home). In March, police officers would move people along if they were sitting on a park bench (as that's not exercise); the second time round things were much less strictly enforced. Rules around forming 'bubbles' with other households also didn't exist in March.

Tier 4 is essentially the same as the November lockdown but you can meet one other person outdoors.

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Covid 12/24: We’re F***ed, It’s Over
henryaj5y20

Cases went from about 20 on September 1 to 370 in  mid November.  Then they *dropped* to 213 before jumping up to 500.

The UK had a national lockdown in November, and lifted it at the start of December.

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2Covid 'Mink variant'
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