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Suppose I sample the genomes of two random humans,  and What information is redundant across these two random variables?...So, for instance, I throw away , then I look at all the other genomes and see that in most places they’re the same - so when I sample my new  I know that it should match all the other genomes in all those places.

I can't really tell what distribution(s) you're talking about here.  You describe G_1 and G_2 as two random humans; wouldn't these then just be two draws from the same distribution of all human genomes?  If not, what distributions are you talking about?  Certainly, for a single human, there's only one genome, not a distribution (presuming you're not talking about chimerism or whatever).  Are you trying to describe parameterized distribution of human genomes, where you have a prior over the parameter values and where you draw repeatedly from the genome distribution, updating your prior over the parameters?