Hello folks! I'm the person who presented the 'expansion x-ray microtomography' approach at the Oxford workshop. I wanted to mention that since that presentation, I've done a lot of additional research into what would be needed to facilitate 1 year imaging of human brain via synchrotron + ExM. I now have estimates for 11-fold expansion to 27 nm voxel size, which is much closer to what is needed for traceability (further expansion could also help if needed). You can find my updated proposal here: https://logancollinsblog.com/2023/02/22/feasibility-of-mappin... (read more)
Hello folks! I'm the person who presented the 'expansion x-ray microtomography' approach at the Oxford workshop. I wanted to mention that since that presentation, I've done a lot of additional research into what would be needed to facilitate 1 year imaging of human brain via synchrotron + ExM. I now have estimates for 11-fold expansion to 27 nm voxel size, which is much closer to what is needed for traceability (further expansion could also help if needed). You can find my updated proposal here: https://logancollinsblog.com/2023/02/22/feasibility-of-mappin... (read more)