Most sources that I read often refer to this overfeeding trial of extra 1000 kcal of saturated (SAT), unsaturated (UNSAT) or carbohydrates (CARBS). Not that many people involved (38), but a good thing is that it is a controlled randomized trial where participants were given the food. Endpoints measured are liver fat content change via two pathways. So not an serious event like CVD or stroke, but a marker (fatty liver) that is easier to measure and an endpoint that we know that is really bad for health. Results: overfeeding with SAT is most harmful, more th... (read more)
Most sources that I read often refer to this overfeeding trial of extra 1000 kcal of saturated (SAT), unsaturated (UNSAT) or carbohydrates (CARBS). Not that many people involved (38), but a good thing is that it is a controlled randomized trial where participants were given the food. Endpoints measured are liver fat content change via two pathways. So not an serious event like CVD or stroke, but a marker (fatty liver) that is easier to measure and an endpoint that we know that is really bad for health. Results: overfeeding with SAT is most harmful, more th... (read more)