A nice graphical guide on COVID-19 vaccines: https://www.nature.com/articles/d41586-020-01221-y
To grow the virus and inactivate them by chemical reagents is the standard setup for (older) influenza vaccine systems that are egg- or cell-culture-based. From such a setup whole-virus- or subunit vaccines can be derived.
Interesting COVID-19 vaccine development landscape publication in Nature.
To produce a vaccine, you will need at least:
In biopharmaceutical production you have two kind of extremes in the facility design:
Of course, everything between those two designs is possible. Both types can be designed to produce multiple products which is referred to as a "multi-product facility". Depending on the automation grade you will need more or less staff with more or less training and experience. For the ramp-up of the facility and for ongoing troubleshooting you will need (highly) educated stuff.
The vaccine production systems can be roughly classified into these variants:
These outlined systems are quite different, and, therefore, the facilities will look different. However, a well-designed multi-product facility should be able to cover a wide range of the possible vaccine types because basic fluid handling and a lot of other steps are similar.
The most similar historical equivalent I can think of is the penicillin production, although there the circumstance where quite different.
Vaccines are one of the most cost-effective medical preventive measures but usually the margins are thin. This is why the investments in such products has not seen the levels of treatments of civilization diseases, e.g., cancer or diabetes.
Edit: Added large scale process to the points at the beginning.
No direct prediction from my side but a link to a report:
The full PDF report (linked on the website) has on page 15 a overview of possible outcomes that could be a basis for discussion.
Link to a/the German source incl. translation: https://www.lesswrong.com/posts/ACyGvQchWzGjGkKgS/coronavirus-open-thread?commentId=TSP5KNPxnSZRM8Sai
See here: https://www.statnews.com/2020/03/19/an-updated-guide-to-the-coronavirus-drugs-and-vaccines-in-development/
Interesting comment on a (maybe) new symptom, i.e., loss of smell and taste for several days, of a COVID-19 infection in an interview of a MD with focus on Virology in Germany:
Google translation of the interesting part:
"Almost all infected people we interviewed, and this applies to a good two thirds, described a loss of smell and taste lasting several days. It goes so far that a mother could not smell the full diaper of her child. Others could no longer smell their shampoo, and food began to taste bland. We cannot yet tell exactly when these symptoms will appear, but we believe a little later in the infection." (emphasize mine)
Sample size: approx. 100 patients, not very severe cases, i.e., no hospitalization (stated in the interview).
German newspaper source: https://www.faz.net/aktuell/gesellschaft/gesundheit/coronavirus/virologe-hendrik-streeck-ueber-corona-neue-symptome-entdeckt-16681450.html
Google translate link to English: https://translate.google.com/translate?hl=en&sl=de&u=https://www.faz.net/aktuell/gesellschaft/gesundheit/coronavirus/virologe-hendrik-streeck-ueber-corona-neue-symptome-entdeckt-16681450.html
However, I am not sure what the base rate of smell and taste loss is during an influenza or common cold infection?
What I know from clean rooms in the biopharmaceutical production is that you avoid there cardboard at all because there is no straightforward way for disinfection (besides the particulate contamination that comes with them). Therefore, one approach is to remove the cardboard as soon as possible and put it away (and wash your hands afterwards).
Edit - Additional comment to make the statement more precise:
There is no straightforward way for disinfection of cardboard without destroying it, i.e., the cardboard soaks in the cleaning agent and will disintegrate.
Monitor the situation, e.g., with dashboards like this: https://www.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6