I guess a deficit in quantitative reasoning is just one of the contributing factors.
Another contributing part, I keep thinking about a lot, is the role of social media during the pandemic. Social media is making money by engaging people. The longer people are on your platform, the more data you can harvest and the more advertisements you can show them, resulting in more revenues. And the more data you have, the better you can target the ads, and so on. The best way to drive up engagement is to promote controversial posts (the more extreme the better, you like it and share it or you don't like it and talk about it). This leads to filter bubbles. By knowing the main orientation of those filter bubbles it is easy to drive up engagement by showing each filter bubble some posts that are aligned to their views (maybe even increasing to more extreme topics and standpoints).
Of course this is not beneficial for the society as a whole and it drives division and is not improving a culture of open discussion, but it is currently a great and more or less unregulated money making machine.
Pair that with a very capitalistic society without a lot of social security nets and a situation that brings people to the edge (i.e., pandemic) and the outlined mechanics from above is running even faster/better (isolated people, increase of fear of the unknown, mental health issues, etc.).
(And hey, you can even use this technology (unofficially) to harm other parties and cause a lot of damage with a fraction of the cost of traditional operations.)
And in the end, the outlined aspect comes down to misaligned incentives.
(Note: Maybe I was reading recently too much about misinformation using natural language processing.)
A nice graphical guide on COVID-19 vaccines: https://www.nature.com/articles/d41586-020-01221-y
To grow the virus and inactivate them by chemical reagents is the standard setup for (older) influenza vaccine systems that are egg- or cell-culture-based. From such a setup whole-virus- or subunit vaccines can be derived.
Interesting COVID-19 vaccine development landscape publication in Nature.
To produce a vaccine, you will need at least:
In biopharmaceutical production you have two kind of extremes in the facility design:
Of course, everything between those two designs is possible. Both types can be designed to produce multiple products which is referred to as a "multi-product facility". Depending on the automation grade you will need more or less staff with more or less training and experience. For the ramp-up of the facility and for ongoing troubleshooting you will need (highly) educated stuff.
The vaccine production systems can be roughly classified into these variants:
These outlined systems are quite different, and, therefore, the facilities will look different. However, a well-designed multi-product facility should be able to cover a wide range of the possible vaccine types because basic fluid handling and a lot of other steps are similar.
The most similar historical equivalent I can think of is the penicillin production, although there the circumstance where quite different.
Vaccines are one of the most cost-effective medical preventive measures but usually the margins are thin. This is why the investments in such products has not seen the levels of treatments of civilization diseases, e.g., cancer or diabetes.
Edit: Added large scale process to the points at the beginning.
No direct prediction from my side but a link to a report:
The full PDF report (linked on the website) has on page 15 a overview of possible outcomes that could be a basis for discussion.
Link to a/the German source incl. translation: https://www.lesswrong.com/posts/ACyGvQchWzGjGkKgS/coronavirus-open-thread?commentId=TSP5KNPxnSZRM8Sai
See here: https://www.statnews.com/2020/03/19/an-updated-guide-to-the-coronavirus-drugs-and-vaccines-in-development/
Interesting comment on a (maybe) new symptom, i.e., loss of smell and taste for several days, of a COVID-19 infection in an interview of a MD with focus on Virology in Germany:
Google translation of the interesting part:
"Almost all infected people we interviewed, and this applies to a good two thirds, described a loss of smell and taste lasting several days. It goes so far that a mother could not smell the full diaper of her child. Others could no longer smell their shampoo, and food began to taste bland. We cannot yet tell exactly when these symptoms will appear, but we believe a little later in the infection." (emphasize mine)
Sample size: approx. 100 patients, not very severe cases, i.e., no hospitalization (stated in the interview).
German newspaper source: https://www.faz.net/aktuell/gesellschaft/gesundheit/coronavirus/virologe-hendrik-streeck-ueber-corona-neue-symptome-entdeckt-16681450.html
Google translate link to English: https://translate.google.com/translate?hl=en&sl=de&u=https://www.faz.net/aktuell/gesellschaft/gesundheit/coronavirus/virologe-hendrik-streeck-ueber-corona-neue-symptome-entdeckt-16681450.html
However, I am not sure what the base rate of smell and taste loss is during an influenza or common cold infection?
What I know from clean rooms in the biopharmaceutical production is that you avoid there cardboard at all because there is no straightforward way for disinfection (besides the particulate contamination that comes with them). Therefore, one approach is to remove the cardboard as soon as possible and put it away (and wash your hands afterwards).
Edit - Additional comment to make the statement more precise:
There is no straightforward way for disinfection of cardboard without destroying it, i.e., the cardboard soaks in the cleaning agent and will disintegrate.