PeterDonis
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Your R is actually the Ricci tensor, not the Riemann tensor. The Riemann tensor has four indices, not two. The Ricci tensor is formed by contracting the Riemann tensor on its first and third indices.
Whether that means 'out of the normal range' for any particular hormone, I don't know. Nobody seems to have the faintest idea what 'normal range' means for these things.
Yes, a better way to put it would be that the bloodstream levels of T3/T4 should be significantly higher when the person is treated and feels better than they were before treatment.
it should probably cause TSH suppression
That would be expected, yes.
What would be ideal would be to figure out the cause of the 'hormone resistance', and fix it, rather than trying to overwhelm it.
Yes, agreed. See below.
It might even be a bad idea to fix it, if it's performing some vital immune defence function.
If... (read more)
Ok, so the "hormone resistance" hypothesis is really something more like: the rate of some key reaction involving T3/T4 is being slowed down by some unknown factor; since we don't know what the factor is, we can't fix it directly, but we can increase the reaction rate by increasing the concentration of T3/T4 in the bloodstream to above normal levels, to compensate for the damping effect of the unknown factor.
This hypothesis makes an obvious testable prediction: that when people with CFS/etc. who are treated with thyroid extract feel better, the T3/T4 levels in their bloodstream should be above normal. Or, conversely, if their bloodstream T3/T4 levels are within the normal range, they should not feel better, even though they are being treated with thyroid extract. I don't know if any existing data has this information.
I have a couple of questions about your hypothesis.
First, as I understand it, you are hypothesizing that there are people who have symptoms of CFS/etc. but normal blood levels of T3, T4, and TSH, who can nevertheless be helped by taking thyroid extract. And your hypothesized explanation for why these people are having symptoms of CFS/etc. is that, even though there are normal levels of T3 and T4 in their bloodstream, those hormones are not getting into their cells where they are actually needed. But if that is the case, how will putting more T3 and T4 into their bloodstream help? It still won't be getting into the cells. It seems to... (read more)
In this case, the Knighian uncertainty cancels out
Does it? You still know that you will only be able to take one of the two bets; you just don't know which one. The Knightian uncertainty only cancels out if you know you can take both bets.
Apologies for coming to the discussion very, very late, but I just ran across this.
If I saw no need for more power, e.g. because I'm already maximally happy and there's a system to ensure sustainability, I'd happily give up everything.
How could you possibly get into this epistemic state? That is, how could you possibly be so sure of the sustainability of your maximally happy state, without any intervention from you, that you would be willing to give up all your optimization power?
(This isn't the only reason why I personally would not choose wireheading, but other reasons have already been well discussed in this thread and I haven't seen anyone else zero in on this particular point.)
when it was realized in dath ilan that business cycles were a thing, the economists probably said "This is a coordination problem", the shadarak backed them, and the serious people got together and coordinated to try to avoid business cycles.
I think this is a feature of dath ilan, not a bug.
Among the serious questions, there are also some questions like this, where you are almost certain that the "nice" answer is a lie.
On the Crowne-Marlowe scale, it looks to me (having found a copy online and taken it) like most of the questions are of this form. When I answered all of the questions honestly, I scored 6, which according to the test, indicates that I am "more willing than most people to respond to tests truthfully"; but what it indicates to me is that, for all but 6 out of 33 questions, the "nice" answer was a lie, at least for me.
The 6 questions were the ones where the answer... (read more)
Is that because you think it's necessary to Wei_Dai's argument, or just because you would like people to be up front about what they think?
Relativity
Recommendation: Spacetime and Geometry
Author: Sean Carroll
This is an expanded version of Carroll's lecture notes on relativity, which he has used to teach courses and which are available for free online (see the "Lecture Notes" tab on the page linked to above). I find it to be an excellent introduction to the subject, which covers the mathematical tools used, the basics of the theory, and the most common applications, all in a straightforward fashion. I have recommended this text (or its corresponding lecture notes) many times on Physics Forums as a reference for people who want a good introduction to the subject.
Other Textbooks Read:
Spacetime Physics, by Taylor & Wheeler. The text that I... (read more)