I have been experiencing something similar recently on semaglutide, although my hypothesis was simply calorie deficit homeostasis. I’d previously dieted and lost 18 lbs without, and the main difference was the willpower required to do it, the fatigue and associated anhedonia was the same. This might be different if you’re not at all tired?
Would “explain this concept to a younger child” be a better classroom assignment?
What was the point about the carpet rods? You seemed like you were going somewhere interesting with that!
FYI, Mox will also be open to LessOnline ticketholders in the week between LessOnline and Manifest. This is more for people who are flying in a few days early and just need a place to get work done, for socializing highly recommend buying a ticket to Arbor summer camp!
FYI, Mox will also be open to LessOnline ticketholders in the week between LessOnline and Manifest. This is more for people who've got a flight out a few days late and just need a place to get work done, for socializing highly recommend buying a ticket to Arbor summer camp!
The code to enter is 1112# ! If you're new to the space, come up to the 4th floor and I, Mattie, or Austin will help you get oriented :)
The idea of kill markets are of course not so new. One prominent example was the practice of paying bounties for Indian scalps which was practiced by various US government and white civilian entities during frontier conflicts against natives. They were not the first to adopt this practice but they were the ones to spread it across the continent. This incentivized wholesale extermination of native nations, and predation on innocents, rather than mere military submission, a common outcome of those frontier wars.
Reminded me of Ozy’s post “The Life Goals of Dead People”, where guilt/anxiety/trauma makes you choose to live smaller and reduce variance
https://open.substack.com/pub/thingofthings/p/the-life-goals-of-dead-people?r=b9s5z&utm_medium=ios
I did follow that turn, I just am confused by the examples you chose to illustrate it with. The first examples of Bell Labs and VC firms I agree match the claim, but not the subsequent ones.
I am imagining an accountability sink as a situation where the person held responsible has no power over the outcome, shielding a third party. So this is bad as in the airline example (Attendant held responsible by disgruntled passenger, although mostly powerless, this shields corporate structure, problem not resolved), and good as in the VC example (VC firm held responsible by investors for profits, although mostly powerless, this shields startup founders to take risks, problem resolved successfully).
And if this is the frame you're using, then I don't see how the ER doctor and ATC controller examples fit this mold?
The putative method by which leucovorin (folinic acid) might be a cure for some subtype of autism is that folate receptor autoantibodies (FRAAs) block normal sources of folate reaching the brain, causing a form of Cerebral Folate Deficiency (CFD). It's claimed that folinic acid is an atypical source of folate which can still reach the brain in someone with those antibodies. On this theory, that subtype of autism is an autoimmune disease.
No conclusive evidence links vaccinations to autoimmune diseases, but conditional on folinic acid working, we should maybe look more closely at what would cause the autoimmune disorder, and update positively on some version of the vaccine theory?