Consumer WGSes hit ~$1000 with Veritas in 2016. In 2018, Dante Labs began offering WGS at ~$600, with a sale of $350.
And we now have a rumor that Illumina will announce a $100 genome in a few months (presumably in early 2019): https://twitter.com/coregenomics/status/1058790189752049664
$100 might be a little questionable here (apparently Illumina has a history of making the most favorable possible assumptions about volume/amortization) but revisiting my original prediction from 7 years ago:
As part of my work for Luke, I looked into price projections for whole genome sequencing, as in not SNP genotyping, which I expect to pass the $100 mark by 2014. The summary is that I am confident whole-genome sequencing will be <$1000 by 2020, and slightly skeptical <$100 by 2020.
I was too pessimistic about SNP genotyping (it was actually more like $50 in 2014, I was completely unaware of UK Biobank at the time or its scale or savings), definitely right about '<$1000 by 2020', and I think I will turn out to be somewhat wrong about WGS being <$100 by 2020: even if Illumina is fudging some numbers for early 2019 at $100, it'll have almost a whole year to drop the cost a little more, and honestly, even if it's actually $110 does it make a difference considering how many things you can use whole genomes for & general medical overhead? You can hardly get some prescription aspirin these days for $100...
Overall self-assessment: I was more right than I had any right to be in that set of predictions given I was using some simple extrapolating and adding some pessimism/mean-reversion. Not bad, past-self!
If it's worth saying, but not worth its own post (even in Discussion), then it goes here.
(I plan to make these threads from now on. Downvote if you disapprove. If I miss one, feel free to do it yourself.)