This is a big list of the youtube videos I find myself linking to people most often. These are all from the same playlist: https://www.youtube.com/playlist?list=PLgx5WuezywJMj_JS47QIqcn8_3UiiEwPs - comment here if you'd like edit access, I give it out readily. I'd love to have people moving the most important and insightful videos towards the beginning. I'd also love to see people clone the playlist and just make their own version.
These vary wildly in topic and difficulty level. I generally do not try to avoid watching things above my level, I just use it as inspiration for how to fill in what I'm missing. If something sounds basic to you, it probably is.
Many of these videos are quite short, many are quite long.
or 10min with 2x speed!
or 5min with 2x speed!
or 15min with 2x speed!
or 7min with 2x speed!
or 10min with 2x speed
As a strict philosophical materialist, this is what made me start believing in math again ;)
20min on 2x speed!
There are several more videos in will ruddick's playlists that go over the various configuration changes to this sim, and he also has a version you can try online
These songs are great openers for a college class on the topics they cover. very worth watching to get a quick rundown of the field. despite being a song. also they're catchy as hell. I can't remember the originals of these songs anymore.
I'd recommend this extension that allows you to conveniently watch videos faster than 2x.
His research just keeps getting wilder. It's so wild I've begun to really wonder how much he's going to turn out to be right about, but his hypotheses and evidence for them are really quite something.
I am reminded of the debate over "junk DNA" and noncoding RNA, i.e. parts of the genome that get transcribed, but never get translated into protein. The null hypothesis is that neither does anything, they are just there because evolution only optimizes things just enough to work, and so there can be genome sections that don't do anything and RNA transcripts that just get recycled. The maximum hypothesis (I have heard this from Ron Maimon and I think from John Mattick) is that the population of noncoding RNAs in a cell, forms an intelligent state-machine that controls everything the cell does. The current understanding seems to be, that noncoding DNA and noncoding RNA do often matter for cell function, but only as a kind of supplement to the old central dogma (DNA -> RNA -> protein), and most of the time they really are epiphenomenal.
The standard paradigm for morphogenesis seems to be a combination of genetic regulatory networks and Turing-style self-organization by chemical gradients, causing cell differentiation to occur in the appropriate parts of the embryo. The null hypothesis about "bioelectricity" would be that it's irrelevant. The maximum hypothesis is that the "body electric" is the dominant factor in morphogenesis, and that e.g. limb regeneration is a matter of appropriately shaping electric gradients in tissue at the regeneration site... A unified approach might look at interactions among chemical gradients, electric gradients, and gene expression. The ion channels are important not just because they create the voltages, but they are also involved in chemical signaling. Perhaps there's an interaction with G proteins.
yeah I think realistically what we're actually seeing is that interaction networks are neuron-like redundant communication of morphogenic targets, and every cell is a complex redundant state machine which communicates using a variety of methods with neighbors. Bioelectricity is one of those network channels, and due to being able to react fast, is an important one, but chemical signaling will also be involved for slower messages or more precise messages or what have you. it does seem like he's shown strong evidence for bioelectric signaling being probably the dominant cell role tag, with other signaling networks being involved in a different role than bioelectric, though this field isn't where I've gone deep and I'm missing a lot of existing knowledge that probably answers many of these questions.