vaš

That's true, yes. Eradication is probably very hard, if not impossible. But I was more talking about speculative future screenings whereby you'd compute some "risk score" as a function of the full genome, select over that, and thereby merely reduce the number of trans people. Of course, it is very much possible that selecting embryos to minimize one kind of "risk" would just increase the rates of other types of problems and reduce genetic variance well beyond "reducing trans people", so this kind of complex screening might not be worth it, either way, for any polygenic trait. It might not be possible to accurately predict the phenotypes of out-of-distribution genotypes at all,... (read more)

In my view:

1. It is plausible that such treatments or screening would, at least initially, be more readily accessible to more affluent people, and thereby, being trans might become a stronger signal that someone is of low economic status than before.

2. A general sense that "this is a disappearing problem" might remove any incentive to work on reducing stigma faced by the still-existing trans people, providing them with better treatment, etc.

Sure, those problems are likely to be neutralized on a societal level by the fact that there will simply be less affected people left. But from the perspective of a single trans person, who obviously cannot benefit from PGT and might not... (read more)