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The easiest way to donate is through every.org.
(Beware, they by default recommend donating 15% to the every.org platform itself. I think that's too much, I would reduce it to 0 if I was donating)
If you want to donate larger amounts or weirder types of assets, reach out to me either on signal at +1 510 944 3235, or via email at habryka@lesswrong.com.
