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If bacteria gave us a tool for bio engineering, have viruses given us a delivery mechanism?

by jmh
20th May 2020
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If bacteria gave us a tool for bio engineering, have viruses given us a delivery mechanism?
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kjz

May 20, 2020

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Yes they have! Adeno-associated viruses (AAV) have been used to deliver gene therapies, with one prominent example being Zolgensma, a treatment for a rare genetic disease called spinal muscular atrophy.

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[-]jmh5y10

Thanks. Interesting. Seems that the term I want is "viral vector".

Clearly some bugs still to work out (bad pun, sorry) but seems like a very promising approach though I think eventually the fix should be something that is also present in off-spring (which currently is probably illegal so and will change the risk assessment needed)

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1kjz5y
Yup, viral vector is the more general term. And you're right, heritable modifications are much more controversial, which is why the Crispr babies got so much attention a little while back.
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If so what is the name for that technology and what would be the right search terms to find the literature?

From bacteria we got CRISPR.