As part of the LessWrong Coronavirus Link Database, Ben, Elizabeth and I are publishing daily update posts with all the new links we are adding each day that we ranked a 3 or above in our importance rankings. Here are all the top links that we added yesterday (March 17th), by topic.
Notion board aggregating mostly project-related news
The goal of COVIDbase is to link people who have skills to relevant projects and to inspire new ideas.
Wolfram's tools and data for C19 visualization
Collection of Wolfram resources relating to C19, including data visualization and mining tools and datasets to run them on
Discussion: are cloth masks useful?
Do masks made from typical clothes do enough to be worth the convenience? Hrothgar concludes they do
Intro to basic science of C19 and treatment/prevention
Gentle guide to the basic science of C19, diagnostics, the course of the disease, and types of treatment one might receive
Small RCT shows promise for chloroquine, w/ or w/o azithromycin
(FRENCH) N=24 study showed patients recovering several days faster with chloroquine, and even faster with azithromycin
Characteristics of 140 Wuhan patients
Fever (91.7%), cough (75.0%), fatigue (75.0%), and gastrointestinal symptoms (39.6%) were the most common clinical manifestations, hypertension (30.0%) and diabetes mellitus (12.1%) were the most common comorbidities. Drug hypersensitivity (11.4%) and urticaria (1.4%) were self-reported by several patients. Asthma or other allergic diseases were not reported by any of the patients. Chronic obstructive pulmonary disease (COPD, 1.4%) patients and current smokers (1.4%) were rare. `
Paper: study of C19 protease for possible drug targets
Scientists testesd C19 M-pro protease to determine its preferences, using a large number of both natural and unnatural amino acides.