leggi

leggi's Comments

Voting Phase of 2018 LW Review (Deadline: Sun 19th Jan)

I've found the review process a good insight into what goes on on LW. From the posts nominated and the comments and feedback they have generated I have more of an understanding of general topics but I have a lot of questions about definitions...

A couple of thoughts:

improving the LessWrong community's longterm feedback and reward cycle.

Feedback risks punishment.

"Reward cycle" is an interesting phrase - More karma sharing between the collective? Or rewarding interactions and the development of ideas/processes/beliefs/understanding through debate and learning?

What is the aim/dream for the book? On a scale of globally-acclaimed to something solid for the collective to hold.

A nomination/review cycle for 2017 (and back) would be worth doing if creating a physical book for wider release.

George's Shortform

If there's different definitions of AGI then that's quite a barrier to understanding generally. Never mind my confusions as a curious newbie.

This feels a really good time to jump in and ask for a working definition of AGI. (simple words, no links to essays please.)

Illness anxiety disorder: how to become more rational?

Movable suggests something located in subcutaneous tissue rather than muscle tissue. Soft, smooth, solitary all 'nice' characteristics for lumps.

You say you've had a heart exam, so assuming cardio. is OK. The lumps are most likely benign - do some research on fibrous lumps/ fibrosis.

And research the diagnostic capabilities of ultrasound before paying for an expensive one.

(House was a comedy about incompetent doctors IMO)

A full history and clinical exam should always be done before expensive tests. - Do it yourself if you want. Start a list of pains and niggles, past illness, injuries, falls, surgery, trauma etc... Feel all over your body for lumps and thickenings, tender spots etc - in all sorts of positions. Positioning can affect the ability to feel some things.

It's a long while since I used ultrasound (and it was an old machine for even back then), but bone reflects ultrasound so over the ribs imaging is commonly distorted as the waves are bounced back. (unless this ultrasound is capable of scanning to a depth of less than skin to ribs).

- - --

A possible explanation:

Chest pain can come from muscle pain. intercostal muscles, rectus abdominis muscles especially. Can be sharp and stabbing. Can be tight or shooting.

The lumps are fibrous, benign thickenings in subcutaneous connective tissue over your pecs. Possibly developed 'to take the strain' when the trapezius muscles aren't sufficiently supportive.

Promotion of my hypothesis/the best advice I can give:

Have a look at this anatomy: main muscles and think about how you use your body, how balanced and aligned are you? Do you have a full range of movement or do you have tensions and restrictions? (I've written a lot more but a few pictures and a bit of self-touching will get you started.)

Give it a bit of thought over some days, feel how you move.

- --

If nothing else, you should be able to find the lumps more easily again if you do decide to get further examinations.

Illness anxiety disorder: how to become more rational?

I am not a doctor and this is not medical advice! To you I am just some random ...

I was a veterinary surgeon so do have some mammalian clinical experience and I do have a lot of lumps over my pecs. I think I can explain them, they are benign. But your lumps are yours - so you first.  

You say duration approx. 18months anxiety. Is that when you first noticed the "lumps"?

When I touch my pectoral muscles, I can feel lumps

Describe the lumps.

Take a deep breath in through your nostrils a few times to relax a little. You'll be fine.

Then really feel the lumps  Number size type distribution  

hard-soft?

smooth-irregular?

solitary-connected?

round-elongated-chain?

fixed-movable?

Let's start there.

On the Loss and Preservation of Knowledge

I'm struggling with clarity in my head using the current labelling:

Living traditions - makes sense.

Dead traditions - Dead naturally brings me to 'dead and gone' - where as they are still being transmitted but have lost their meaning. I think corrupted, lost in translation ....

Lost traditions - works better for me when I've re-labelled dead traditions as corrupted (or another better word that hasn't jumped to me yet).

Phage therapy in a post-antibiotics world

I only know about colloidal silver as a topical treatment (a cream for wounds that I think I only ever prescribed twice). Are you talking about other usage methods? My fantasy flesh-eating multi-resistant infection is easily accessible - silver was a back-up thought after rushing to the kitchen for salt and garlic.

A bit of background info. about bacteriophages would be useful in your post. For general interest and understanding. The following is from the bottom of the case study here:

Derived from the Greek words meaning “bacteria eater,” bacteriophages are ancient and abundant — found on land, in water, within any form of life harboring their target. According to Rowher at San Diego State University and colleagues in their book Life in Our Phage World, phages cause a trillion trillion successful infections per second and destroy up to 40 percent of all bacterial cells in the ocean every day.
Thousands of varieties of phage exist, each evolved to infect only one type or a few types of bacteria. Like other viruses, they cannot replicate by themselves, but must commandeer the reproductive machinery of bacteria. To do so, they attach to a bacterium and insert their genetic material. Lytic phages then destroy the cell, splitting it open to release new viral particles to continue the process. As such, phages could be considered the only “drug”’ capable of multiplying; when their job is done, they are excreted by the body.

The potential for targeting individual bacterium in patients - fantastic.

The potential for patents on individual bacterium - frightening.

The thought that there's all these 'specific bacterial destroyers' out there - weird and wonderful.

I really feel the need to hope in writing that phage therapy is something that's developed in the spirit of co-operation and sharing. To treat patients with infections, not for generating profits at the expense of people who need help.

For better health outcomes we shouldn't forget the basics: "Bugs" are ubiquitous. Strong immune systems to fight the baddies are more likely with healthy lifestyles in natural environments - unpolluted and full of all the other organisms we evolved encased in. If we're all about the good bugs, the bad bugs can't get established so easily.

Since figuring out human values is hard, what about, say, monkey values?

My background: I've spent a lot more time with animals than rational humans.

To point me in the right direction before trying to write more - I would like a definition for "values" to work with.

An instant find via images - human values. Anywhere near?!

Clarifying "AI Alignment"

I'm not tech. savvy and am well aware that maybe it's a lack of understanding that lets me live without fear of AI but it seems an important issue round here and I would like to have some understanding. And a little understanding of my perspective - I grew up in shadow of the Cold War i.e. mutually assured destruction in 6 minutes or less (it might have been 12 minutes - I can't quite remember anymore).

This post caught my eye on the review list.

I need to clarify something before reading forward.

getting your AI to try to do the right thing,

Is: 'getting your AI to try to do the WANTED thing' be the accurate wording?

The usage of "right" adds a dimension of morality in my mind that doesn't come with "want".

100 Ways To Live Better

Well worth reading - some good advice, some funny bits! Will keep my smiling for a while. Thanks.

Phage therapy in a post-antibiotics world

2 cases that I'm aware of successfully treated with phage therapy: here and here. It's a promising field.

Some historical info. (and a bit of an insight into medical discoveries/research's ups and downs.)

- - --

The overuse of antibiotics is shocking on a world-wide scale. From "growth promoters" and "disease prevention" in farm animals to the "just in case/covering my ass/the patient won't fk-off without them" dispensing/being able to buy over-the-counter without a prescription.

I've seen infections spread and sepsis overwhelm animal patients within hours where the infection too fast for antibiotics to counter (euthanasia is only realistic clinical option).

I've often wondered what I'd do if infected with an antibiotic-resistant bacterial infection. My imaginary scenario starts local and external - where I'd use topical sodium chloride, freshly crushed garlic, colloidal silver (alternating or mixed I don't know). With the phase "don't fk about with debridement, just amputate" ready for anything that's spreading. Whilst eating more fresh garlic and drinking high doses of tincture of Echinacea (potential to boost immune system and if not the alcohol component might be quite welcome during my final hours - partly said in jest also deadly serious.)

Anyway, an interesting post to share.

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