Case study: Melatonin

gwern

I discuss melatonin's effects on sleep & its safety; I segue into the general benefits of sleep and the severely disrupted sleep of the modern Western world, the cost of melatonin use and the benefit (eg. enforcing regular bedtimes), followed by a basic cost-benefit analysis of melatonin concluding that the net profit is large enough to be worth giving it a try barring unusual conditions or very pessimistic safety estimates.

Full essay: http://www.gwern.net/Melatonin

I discuss melatonin's effects on sleep & its safety; I segue into the general benefits of sleep and the severely disrupted sleep of the modern Western world, the cost of melatonin use and the benefit (eg. enforcing regular bedtimes), followed by a basic cost-benefit analysis of melatonin concluding that the net profit is large enough to be worth giving it a try barring unusual conditions or very pessimistic safety estimates.

Full essay: http://www.gwern.net/Melatonin

I am microdosing, 300mcg plain + 300mcg time-release, both from LEF. Currently trying doubling the time-release dosage to see if that works better. More than 400mcg up-front did not work well. In general, people trying melatonin are advised to try microdoses.

In general, people trying melatonin are advised to try microdoses.

That's definitely something I noticed in the anecdotes: people with positive experiences seem to mention switching to 1mg doses and not experimenting.

I'm going to strengthen the language in my melatonin essay dealing with dosage, and add some reminders to myself to do more blind experiments with differing doses when I run out of my current melatonin pill mixes.

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Case study: Melatonin

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Case study: Melatonin

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