links 3/2/26: https://roamresearch.com/#/app/srcpublic/page/03-02-2026

• https://arxiv.org/abs/2602.07164 more effective way to elicit "in character" personalities from LLMs 
• https://blog.egan.bio/p/reviving-estrogen-replacement-therapy  overview on why hormone therapy for menopause is losing its black-box label (tl;dr: it's not a totally unreasonable choice)
• https://www.owlposting.com/p/neurotechnology-for-cancer-ben-woodington Abhishaike Mahajan interview with the founders of Coherence Neuro, which uses neuromodulation to disrupt (mostly brain) tumors. neurotransmitters can be tumor growth factors! 
• https://en.wikipedia.org/wiki/Fixed-income_attribution#Modeling_the_yield_curve functions that define the yield curve for bonds 
• https://lydialaurenson.substack.com/p/social-contracts-moral-order-weaving Lydia Laurenson on "missing stair" type dynamics, how hard it is to enforce norms against bad actors in a community
• https://www.hyperdimensional.co/p/clawed Dean Ball is sticking his neck out to do the right thing here 
• https://www.clinicaltrialsabundance.blog/p/ai-wont-automatically-accelerate sorry Dario Amodei, AI can't make all clinical trials take under a year; sometimes you need follow-ups longer than that for the actual course of disease to become clear! this is crazypants and we need to keep in mind the actual places there's room for improvement on trial times -- reducing purely regulatory delays, or procedural time (like patient recruitment time) as opposed to medically-relevant follow-up time, and finding surrogate endpoints where good ones exist. (I kinda hate surrogate endpoints cause so many suck, but yeah, clearly, when you find a good one it will speed up trials substantially.) Ruxandra Tesloianu bringing the common sense and much-needed urgency, as usual.
• https://marginalrevolution.com/marginalrevolution/2026/02/if-you-have-the-right-to-die-you-should-have-the-right-to-try.html right-to-try is the least-good and most popular form of medical deregulation, IMO, but it is still correct. Ruxandra Tesloianu again.
• https://read.technically.dev/p/how-are-companies-using-ai survey of how companies are using AI
• https://www.economicforces.xyz/p/we-dont-need-to-just-make-up-fantasy solid economics based takedown of the Citrini piece

• https://www.gleech.org/enhance I think I buy this, by Gavin Leech; nobody will ever acknowledge that the transhumanists were right, they will simply adopt "better-than-well"/human-augmentation technologies piecemeal, as those technologies become practical, safe-enough, and accessible.