You might want to edit the title to “Four major problems with neuroscience”: as it is worded now, I took it to be about unanswered questions.
Very useful information and incredibly relevant for, among other things, rationality testing. I have some experience with these kinds of effects from my research on motor control, but it's good to keep them in the forefront of one's mind when designing studies.
A discussion of four errors which lead to false positives-- neglecting maturation (that brains change with time, even without intervention, learning effects (people who take a test more than once get better at it), regression to the mean (people who are unusually good or bad at something will probably have a more average score on subsequent attempts), and the placebo effect.
The link above is a summary of a lecture which isn't playing for me, so any further information about the lecture would be greatly appreciated.