I think the general strategy should be extreme diversification across asset classes. It might be that the stock market itself goes out of business, and stocks themselves cease to exist, on average once every thousand years. How would we know? There haven't been stock markets that long. And for a non-cryonicist who expects to have money in the market for maybe 50 years tops, that's not a problem. For a cryonicist who expects to have money in the market for a thousand years, that is actually a huge problem. So I would say put some money in the stock market. Put some money in REITs. Put some money in cryptocurrency. Put some money into artwork and coin collecting. Put some money in things that have a record of holding value for a thousand years - precious metals and gems, plots of land, water rights. Anything else you can think of that seems not stupid. This way, if any particular class of stuff goes bust, you've still got most of your capitol. If it all goes bust, well, probably nobody will be left to revive you anyway so it won't matter.
As a separate strategy, also put some money into biotech and AI specifically, both because that might lead to people figuring out how to revive you, and because if people do figure out how to revive you, it will probably be because biotech and AI have been successful.
Am just thinking about this now, so not high confidence.
I'm thinking a total market cap index of all publicly traded companies in the world -- unless some stock exchanges are really sketchy for some reasons (I'm aware "sketchy" is ill-defined).
Also maybe a fraction (10%?) stored in a total market cap of deflationary currencies (decentralized ones I suppose, as for centralized ones it's generally harder to tell if they will become inflationary) as they will presumably become more in demand, in the short term as the economy might transition to them, but also in the long term as the population grows and so those the demand for currency (although if minds start running faster, I think that would decrease the value of currencies as they would be traded more often).
Maybe worlds in which reanimation is possible is correlated with other technological development, and so that might also inform some investments, but not sure which ones, and that starts adding a lot of complexity, at least while we don't have large prediction markets.
I'm also thinking those investment don't need to be liquid at all, and REITs often have a higher return because they are less liquid than stocks (AFAIU); so if this is true, then maybe having a lot of investments in REITs would also be beneficial. (2021-05-08 update: this is also true of other investment vehicles, like loans)
Assume this policy will be followed by someone else, potentially for centuries, unless your cryonics revival timeline is shorter.
You can answer differently for different trusts; notably: