Link: Simulating C. Elegans

by Sniffnoy1 min read20th Nov 20142 comments

22

Personal Blog

http://radar.oreilly.com/2014/11/the-robotic-worm.html

Summary, as I understand it: The connectome for C. elegans's 302-neuron brain has been known for some time, but actually doing anything with it (especially actually understanding it) has proved troublesome, especially because there could easily be relevant information about its brain function not stored in just the connections of the neurons.

However, the OpenWorm project -- which is trying to eventually make much more detailed C. elegans simulations, including an appropriate body -- recently tried just fudging it and making a simulation based on the connectome anyway, though in a wheeled body rather than a wormlike one.  And the result does seem to act at least somewhat like a C. elegans worm, though I am not really one to judge that.  (Video is here.)

I'm having trouble finding much more information about this at the moment.  I don't know if they've actually yet released detailed technical information.

2 comments, sorted by Highlighting new comments since Today at 7:27 PM
New Comment

I haven't thought about this much since 2011 [1] but I think what they've done in hardware is something previously people have done in software. It doesn't sound like they (or anyone else) has been able to demonstrate learning on their simulated nematode.

EDIT: Expanded this into a post.

[1] I looked into nematode simulations several years ago, and talked to a few people including Stephen Larson at the Open Worm project: http://www.jefftk.com/p/whole-brain-emulation-and-nematodes

Thanks, I didn't think to check about people doing this in software earlier.