Your childhood home probably has greater total value to you than it would to a buyer. This particular house is important to you, and the odds of not losing a ton of money on replacing this particular house if you change your mind later are miniscule. Consider renting it, perhaps through an agency, for an amount that would allow you to rent something smaller in a safer location.

The exceptions which come to mind, where holding onto a house would be throwing money away long-term, are if it's a manufactured in a trailer park with lot rent, or if it's in an expensive HOA.

I think you probably shouldn't rent to someone you know. "Move back into the property you own" is a good safety net for if your finances change suddenly and substantially. If you retain ownership, it decreases the probability that you will have no housing at all in many worst-case scenarios. Choosing not to renew the lease on a good tenant would be hard; declining to renew on a friend who was counting on you for their housing would be much harder.

It could be a good compromise to try to find your happy price -- if someone offered you $1 for the house, you would laugh at them. If someone offered you $1B for the house, you would likely accept immediately. Somewhere in between those extremes is a price that would almost certainly get it sold fast; above that is a price that would be enough money to soothe the heartbreak of losing a childhood home. You could try listing the house at a price based solely on your feelings rather than market analysis, see whether it sells in a timely manner, and rent it out if it doesn't.

Some assorted thoughts:

Have you considered holding on to your childhood home and renting it to someone you know?  I assume it hurts more to sell it than it would hurt to know it is giving a friend a roof (at a potentially good price).  

I expect continuing to live in an area that has regular shootings is unlikely to be high EV but I don't know your life.  Do you consider it to contain your peer group?  Would you be better suited living in a different region of your city/a different city?  

On concealed carry: getting in to gun fights is very unlikely to be maximizing your EV.  You should almost definitely get out of where you are if this is a well founded concern (e.g. the shooting you are mentioning was not a fluke).  

Also on concealed carry- the best tool for self defense if the one you actually have with you when you need it.  Most instances I know of people in my peer group who have felt like they needed to defend themselves/were escalated against have not been happened when they were able to predict beforehand (likely because they avoid situations that they expect to need to defend themselves in preemptively, as you say).  I think you should strive to carry almost all the time it is legal to do so (given you are comfortable with the idea in the first place).  If it is known to be costly to defect against you and/or people like you, people are less likely to do so in the first place.
Is your carry piece comfortable?  I personally went the route of not carrying a firearm for a while even though I was licensed to do so because I had convinced myself that a full size was useful/it was lame to carry a smaller handgun.  It may have been useful, but it doesn't matter how theoretically useful it is if it's also uncomfortable and prints more than I like.  I have since gotten over my pride on that point and now regularly carry a subcompact (rather than occasionally carrying a full size) almost every time it is legal for me to do so.  (Generally speaking, losing weight has also made it much more comfortable to carry and trying different carry positions helped me find my currently preferred carry position at 1 o'clock)

On vibes: move!  it really sounds like you are staying where you are due to intertia rather than actually feeling like it is where you want to be.