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No noticeable effects from vitamin D (both with and without K2), even though I used to live somewhere where the sun barely shines and also I never went outside, so I was almost certainly deficient.
I tried Selenium (200mg) twice and both times I felt like utter shit the next day.
Glycine (2g) for some odd reason makes me energetic, which makes it really bad as a sleep aid. 1g taken a few hours before bedtime is substantially less disruptive to sleep, but I haven't noticed substantial improvements.
Unlike oral phenylephrine, intranasal phenylephrine does things, albeit very temporarily, and is undeniably the most effective thing I've tried, though apparently you're not supposed to use it too often, so I only use it when it gets really bad.