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Up-to-date advice about what to do upon getting COVID?

by DanielFilan1 min read19th Jun 20218 comments

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Covid-19Practical
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LessWrong has hosted a few posts that at least in part tell people what they should do upon getting COVID. That being said, they don't seem to have been updated since last March, and presumably more must be known now. The topic is newly relevant now that the delta variant is spreading in many locations, with vaccination rates being low in most countries.

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The recommendation from the FLCCC is "up-to-date advice" (whether or not you believe them is of course up to you):

Early At Home Treatment Protocol

For adults > 18 years and >40 kg/90 lbsIvermectin24 mg – daily for 5 days In the setting of poor clinical response, advanced disease, or obesity, higher doses should be used (target 0.4–0.6 mg/kg)

Melatonin 6 mg at night for 5 days

Aspirin (ASA)80 mg/day (unless contraindicated)

Anti-septic mouth wash Three times daily (gargle do not swallow); if available

[Epistemic status: I am not a doctor. Things I've heard may be incomplete or out of date.]

If you think it might be COVID-19, get tested ASAP to make sure it's not just a cold. Talk to a doctor. We're well past the point where the hospitals were overwhelmed in the U.S. Treatments should be much easier to get now.

There are monoclonal antibody treatments with Emergency Use Authorization. Even mild cases of COVID-19 seem to cause lung and brain damage, so it's best to get treated as soon as possible, to prevent any more damage. Many have reported long-term effects from the disease.

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Someone could look into Ivermectin, and other claims made by the FLCCC and friends.

I wonder why other antivirals(faviparivir, oral remdesivir) aren't getting more attention compared to ivermectin.

https://blogs.sciencemag.org/pipeline/archives/2021/06/07/ivermectin-as-a-covid-19-therapy is one of the better, current overviews of Ivermectin.  Basically, we don't have enough information.

It had proven antiviral effect against SARS-CoV-2 in cell cultures, but it required doses high enough to be toxic. I've heard of some cases where people self-administered veterinary Ivermectin doses intended for horses and had to be hospitalized. I think this is the reason it's being censored on social media.

But might it be effective at lower doses or in combination with other drugs? Last I heard, that was still under investigation and the evidence was not yet conclusive. My information could be out of date though.

There seem to be meta studies that support it and meta studies that don't. The decision about whom to believe isn't easy.