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Drug legalisation is probably the best way to prevent fentanyl deaths. Many of the people who are fentanyl addicted are addicted because they wanted to buy other drugs buy got them laced with fentanyl. Drug legalisation will allow for quality control and end the lacing with fentanyl.
Now, nitazene which is even more potent than fentanyl gets added and might produce similar effects as fentanyl where people die to nitazene overdose.
If the US wants to actually prevent those deaths drug legalization that allows for quality control is the step forward that would work.