[ Question ]

How dangerous is it to test a vaccine without animal trials?

by Yoav Ravid1 min read14th Mar 20204 comments



I saw the idea a few times (including on LW), and support it, to do/allow human trials for CoronaVirus vaccine without animal trials.

My question is - how dangerous is it for a person to volunteer to test a vaccine (both with and without animal trials)?

How dangerous is it compared to getting the virus itself?

How should someone decide whether to volunteer?

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US volunteers to test first vaccine according to this article BBC

Dr John Tregoning, an expert in infectious diseases at Imperial College London, UK, said: "This vaccine uses pre-existing technology.
"It's been made to a very high standard, using things that we know are safe to use in people and those taking part in the trial will be very closely monitored.
"Yes, this is very fast - but it is a race against the virus, not against each other as scientists, and it's being done for the benefit of humanity."

There is a non zero risk of death. There have been cases where some candidates had severe permanent damage and it took a while to figure out why. We are all slightly different.

Even with animal trials there is a risk. I do not think there is an answer to your question.