I'll be driving north from San Diego, can provide a ride, and would enjoy conversation in the car. To arrange a ride, go to my user page and send me a private message by clicking on the "Send message" button just to the right of my name :-)
It's a social gathering for anyone interested in discussing anything relevant to the LW community. I personally have been part of discussing rationality in general, cryonics, existential risk, personal health, and cognitive bias (among other topics) at the 2 meetups I've been to. It's a good excuse to meet some other folks and trade ideas, start projects, etc.
I don't think we have an agenda organized for this one. But if you're curious, take a look at the comments from the September SoCal meetup for an idea about what was discussed and what people thought was good/bad/interesting about it.
We're having the third SoCal LessWrong meetup this Saturday, the 23rd. It'll be held at this IHOP in Irvine, from 1PM to 8PM, in the upstairs meeting area.
For those that haven't yet come, the last two were quite successful bringing 13 and 16 people respectively, and there was plenty of intelligent and friendly discussion.
Make sure to comment if you have suggestions for how to improve on the last one, if you can give/need a ride, or just to say you're coming.